by SmartTots | Jun 29, 2021 | Research Articles
Abstract Background There is concern that maternal anesthesia during pregnancy impairs brain development of the human fetus. Xenon is neuroprotective in pre-clinical models of anesthesia-induced neurotoxicity in neonates. It is not known if xenon also protects the...
by SmartTots | Jun 29, 2021 | Research Articles
Abstract Purpose of review Long-term behavioural and cognitive impairments after exposure to general anaesthetics during infancy is an intensely investigated and controversial topic. Recent clinical studies with prospective assessments associate exposure with...
by SmartTots | Jun 29, 2021 | Research Articles
Abstract Infants and young children are in a period of rapid neurodevelopment, making them more vulnerable to neurotoxic agents. A topic of much debate is how persistent and pervasive cognitive delays are for children exposed to anesthesia at a young age. The US Food...
by SmartTots | Jun 29, 2021 | Research Articles
Abstract Purpose of review Despite real advances in paediatric anaesthesia management, such as a growing awareness of the relevance of anaesthesia conduct as well as of the lack of evidence for neurotoxicity of anaesthetic agents, it must be said that there are still...
by SmartTots | Jun 28, 2021 | Research Articles
Background Two prior population-based (children born in Olmsted County, MN), retrospective cohort studies both found that multiple exposures to anesthesia before age 3 were associated with a significant increase in the frequency of attention-deficit hyperactivity...
by SmartTots | May 23, 2021 | Research Articles
Moderated by SmartTots Medical Officer, Dean Andropoulos, MD Pre-Clinical Research: What are the priorities? Laszlo Vutskits, MD, PhD Challenges with Clinical Studies and Update on the T-REX Trial -Andrew Davidson, MBBS, MD, FANZCA Clinical Anesthetic Neurotoxicity:...
